clinical comparison of coronally advanced flap combined with amniotic membrane or subepithelial connective tissue in treatment of miller’s class i and ii gingival recessions: a split mouth study.

background and aim: the aim of the present study was to compare coronally advanced flap (caf) with amniotic membrane to caf with connective tissue graft (ctg) in the treatment of miller’s class i&ii; gingival recessions. materials and methods: 11 systemically healthy patients, with 30 miller’s class і and іі gingival recessions ≥3 mm, were selected and randomly divided into two equal groups. gingival recessions in the control group were treated with coronally advanced flap and ctg, and in the test group with caf and amniotic membrane. the clinical parameters including: probing depth (pd), clinical attachment level (cal), recession depth (rd), recession width (rw), and keratinized tissue width (wkt) were measured at baseline, 1, 3, and 6 months postoperative. a p value <0.01 was considered significant. results: rd, rw, cal, and mgj position changed significantly between baseline and 1 month postoperatively (p<0.01) in both groups and remained stable at 3 and 6 month follow ups. there were no statistically significant differences in pd and wkt between baseline and 1, 3, and 6 months postoperatively. the mean root coverage at 6 month period was 75.5% and 63.1% for the control and test groups, respectively. the mean rd reduction of 2.63±0.63 mm and 2±1.4 mm were achieved for the control and test groups respectively. conclusions: the findings of the present study demonstrated that although use of amniotic membrane resulted in decreasing surgical time and patient morbidity, but superior results were achieved by using ctg.